MenoTime™ Live in market

Know your patient's ovarian age.

MenoTime™ is the first and only ovarian age clock and time to menopause predictor, validated on clinical data.

FSH · AMH · E2 Ovarian age + time to menopause
MenoTime™ · Ovarian-Age Report Clinical-grade
38.4
Ovarian Age · yrs
Chronological 41.0
Time to menopause
~9.2 yr
95% confidence
±1.5 yr
Publishedin Menopause, the journal of the Menopause Society
TRIPODvalidated three independent ways
CDSClinical decision support tool, not a diagnostic device

Live today. We partner with telehealth, clinics, and labs.

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Why ovarian age

The ovary is a vital sign.

The ovary is the #1 lever of female healthspan, shaping risk across the whole body, from cardiometabolic disease to bone and cognitive health. Until now, there has been no good biomarker to read it.

Time the perimenopause window

Catch the time-sensitive window for hormone therapy initiation, before symptoms and downstream risk take hold. MenoTime stages the transition and times the conversation.

Treatment timing

Guide fertility decisions

Inform egg-freezing timing, IVF versus IUI versus natural conception, and oncofertility planning with an individualized read on the ovarian reserve trajectory.

Reproductive

Stratify cardiometabolic risk

Spot rising cardiometabolic risk earlier. Ovarian age adds a signal no current biomarker delivers, guiding preventive cardiology and screening cadence.

Risk assessment

Inform bone and cognitive care

Schedule bone-density screening, counsel on osteoporosis prevention, and contextualize cognitive health timing as estrogen declines through the transition.

Long-term healthspan
How MenoTime works

Analyzes the bloodwork you already run.

MenoTime is software that reads the bloodwork you are already doing in clinic to produce a result. No new testing. No workflow disruption.

Step 01

One routine blood draw

A single standard hormone panel, drawn once in routine practice. No new collection protocol and no new equipment.

FSHAMHE2
Step 02

The model decodes ovarian age

Our patent-pending model returns ovarian age and time to menopause, with 95% confidence intervals on every prediction.

Patent-pending ML
Step 03

Deliver a report

An easy-to-read, clinical-ready report returned instantly via simple API or reporting portal.

APIPortal
Clinical decision support tool
The evidence

Validated on clinical data.

A clinical-grade predictor with comparable accuracy to existing clinical risk assessments.

40K+
Datapoints
Built and validated on longitudinal data, with final menstrual period dates recorded down to the day.
~1.5 yr
Accuracy
Mean absolute error predicting time to menopause, at any horizon, on par with Framingham, ASCVD and FRAX.
Published
Abstract
Published in the Menopause Journal, the official journal of the Menopause Society.
TRIPOD
Validated
Validated three independent ways: a held-out test set, 5-fold cross-validation, and 500 bootstrap resamples.
Methodology

A survival-analysis model built on gradient-boosted survival trees, running over 100,000 conditional pathways per patient. It is not generative AI and not a black box. Every prediction returns a 95% confidence interval and a ranked list of the biomarkers driving it.

Reference Humbert-Droz, M., Kumar, K., Stevenson, R., & Lee, M. (2025). MenoTime: Predicting time-to-menopause and estimating ovarian age using serum biomarker-informed machine learning. Menopause, 32(12), Abstract.
Medical advisory board

Backed by leaders in women's health.

MenoTime is guided and used by clinicians across OB/GYN, reproductive endocrinology, oncology, longevity, and machine learning.

NC
Dr. Natalie Crawford, MD
Double board-certified OB/GYN & REI. Host, 'As a Woman' podcast.
AK
Dr. Amy B. Killen, MD
Longevity & regenerative medicine. Co-founder, Humanaut.
SR
Prof. Sirisha Rambhatla, PhD
Director, Critical ML Lab, University of Waterloo.
In the words of our clinical inner circle
Finally… ovarian age decoded. MenoTime gives women the power to turn hidden biology into better health outcomes and a longer life.
LGLabib Ghulmiyyah, MD, FACOGDouble Board Certified OBGYN, Maternal Fetal Medicine
Timeless Biotech's science-forward approach to ovarian aging feels genuinely groundbreaking. MenoTime is poised to become an essential tool for women, helping us understand, support, and even hack the ovarian aging process with clarity and confidence.
CTCynthia Thurlow, NPNurse Practitioner & Women's Health Expert
MenoTime gives focus where it is long overdue. It is a chance to improve women's health through menopause and positively influence their long-term trajectory, including cognitive health.
SKSita Kedia, MD, MPH, FAHSChief Medical Officer, Palm Health
MenoTime offers meaningful clarity during a stage of life that can feel uncertain. By providing insight into ovarian age, it lets us personalize prevention, guide medication management, and support long-term quality of life.
ALArti Lakhani, MDHematologist Oncologist, Director of Integrative Medicine
MenoTime gives women real, science-based insight into how their ovaries are aging. Instead of guessing, we can finally understand the menopause timeline and act early to protect hormone balance, brain and metabolic health, and longevity.
MGMayoni Gooneratne, MBBSFounder & Medical Expert, Human Health
Collagen declines by nearly 30% in the first five years of menopause. If we know when that transition is starting, we can prevent the deficits before they take hold instead of just reacting to symptoms. With MenoTime, women gain the ability to protect skin, bone, brain, and heart health.
KDKay Durairaj, MD, FACSFacial Plastic Surgeon

As seen in

Business Insider USA Today Longevity Technology Flow Space Business Insider USA Today Longevity Technology Flow Space
Get started

Give your patients a number where there used to be a guess.

MenoTime is live and onboarding new clinics. Add the world's only ovarian age clock to the panel you already run.